The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ
The ARID1A-containing SWI/SNF complex operates as an inhibitor of the pro-oncogenic transcriptional coactivators YAP and TAZ; this interaction is regulated by cellular mechanotransduction.
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
31 October 2018
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| In: |
Nature
Year: 2018, Volume: 563, Pages: 265-269 |
| ISSN: | 1476-4687 |
| DOI: | 10.1038/s41586-018-0658-1 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1038/s41586-018-0658-1 Verlag, Volltext: https://www.nature.com/articles/s41586-018-0658-1 
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| Author Notes: | Lei Chang, Luca Azzolin, Daniele Di Biagio, Francesca Zanconato, Giusy Battilana, Romy Lucon Xiccato, Mariaceleste Aragona, Stefano Giulitti, Tito Panciera, Alessandro Gandin, Gianluca Sigismondo, Jeroen Krijgsveld, Matteo Fassan, Giovanna Brusatin, Michelangelo Cordenonsi & Stefano Piccolo |
| Summary: | The ARID1A-containing SWI/SNF complex operates as an inhibitor of the pro-oncogenic transcriptional coactivators YAP and TAZ; this interaction is regulated by cellular mechanotransduction. |
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| Item Description: | Gesehen am 09.04.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1476-4687 |
| DOI: | 10.1038/s41586-018-0658-1 |