Hybridization and reaction-based fluorogenic nucleic acid probes
We developed fluorogenic probes, which are photoactivated in the presence of specific nucleic acid templates with the release of fluorescent dyes. This templated reaction can be used to target specific nucleic acids in complex mixtures. We further demonstrate that this reaction can be monitored by s...
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| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2012
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| In: |
Chemical communications
Year: 2012, Jahrgang: 48, Heft: 77, Pages: 9664-9666 |
| ISSN: | 1364-548X |
| DOI: | 10.1039/C2CC33827K |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1039/C2CC33827K Verlag, Volltext: https://pubs.rsc.org/en/content/articlelanding/2012/cc/c2cc33827k 
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| Verfasserangaben: | Subrata Dutta, Benjamin Flottmann, Mike Heilemann and Andriy Mokhir |
| Zusammenfassung: | We developed fluorogenic probes, which are photoactivated in the presence of specific nucleic acid templates with the release of fluorescent dyes. This templated reaction can be used to target specific nucleic acids in complex mixtures. We further demonstrate that this reaction can be monitored by single-molecule fluorescence imaging. |
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| Beschreibung: | Gesehen am 11.04.2019 |
| Beschreibung: | Online Resource |
| ISSN: | 1364-548X |
| DOI: | 10.1039/C2CC33827K |