Hybridization and reaction-based fluorogenic nucleic acid probes
We developed fluorogenic probes, which are photoactivated in the presence of specific nucleic acid templates with the release of fluorescent dyes. This templated reaction can be used to target specific nucleic acids in complex mixtures. We further demonstrate that this reaction can be monitored by s...
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| Autori principali: | , , , |
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| Natura: | Article (Journal) |
| Lingua: | inglese |
| Pubblicazione: |
2012
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| In: |
Chemical communications
Year: 2012, Volume: 48, Fascicolo: 77, Pages: 9664-9666 |
| ISSN: | 1364-548X |
| DOI: | 10.1039/C2CC33827K |
| Accesso online: | Verlag, Volltext: https://doi.org/10.1039/C2CC33827K Verlag, Volltext: https://pubs.rsc.org/en/content/articlelanding/2012/cc/c2cc33827k 
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| Note sull'autore: | Subrata Dutta, Benjamin Flottmann, Mike Heilemann and Andriy Mokhir |
| Riassunto: | We developed fluorogenic probes, which are photoactivated in the presence of specific nucleic acid templates with the release of fluorescent dyes. This templated reaction can be used to target specific nucleic acids in complex mixtures. We further demonstrate that this reaction can be monitored by single-molecule fluorescence imaging. |
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| Descrizione del documento: | Gesehen am 11.04.2019 |
| Descrizione fisica: | Online Resource |
| ISSN: | 1364-548X |
| DOI: | 10.1039/C2CC33827K |