Towards synchrotron phase-contrast lung imaging in patients: a proof-of-concept study on porcine lungs in a human-scale chest phantom

This proof-of-concept study on a human-scale chest phantom and fresh porcine lungs with artificial pulmonary nodules demonstrates that local-area in-line free propagation phase-contrast synchrotron tomography of fresh porcine lungs can be performed with an acceptable X-ray dose that would allow for...

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Main Authors: Wagner, Willi Linus (Author) , Wünnemann, Felix (Author) , Biederer, Jürgen (Author) , Konietzke, Philip (Author) , Stiller, Wolfram (Author) , Wielpütz, Mark Oliver (Author) , Kauczor, Hans-Ulrich (Author)
Format: Article (Journal)
Language:English
Published: 2018
In: Journal of synchrotron radiation
Year: 2018, Volume: 25, Issue: 6, Pages: 1827-1832
ISSN:1600-5775
DOI:10.1107/S1600577518013401
Online Access:Verlag, Volltext: https://doi.org/10.1107/S1600577518013401
Verlag, Volltext: https://journals.iucr.org/s/issues/2018/06/00/mo5184/
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Author Notes:Willi L. Wagner, Felix Wuennemann, Serena Pacilé, Jonas Albers, Fulvia Arfelli, Diego Dreossi, Jürgen Biederer, Philip Konietzke, Wolfram Stiller, Mark O. Wielpütz, Agostino Accardo, Marco Confalonieri, Maria Cova, Joachim Lotz, Frauke Alves, Hans-Ulrich Kauczor, Giuliana Tromba and Christian Dullin
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Summary:This proof-of-concept study on a human-scale chest phantom and fresh porcine lungs with artificial pulmonary nodules demonstrates that local-area in-line free propagation phase-contrast synchrotron tomography of fresh porcine lungs can be performed with an acceptable X-ray dose that would allow for future application in patients while providing spatial-resolution magnitudes higher than currently available clinical computed tomography scanners.
Item Description:Gesehen am 16.04.2019
Physical Description:Online Resource
ISSN:1600-5775
DOI:10.1107/S1600577518013401