TFAP2E-DKK4 and chemoresistance in colorectal cancer: reply
Patients whose tumors showed methylation and decreased expression of the gene TFAP2E were more than five times as likely as patients with normal TFAP2E gene expression to have resistance to fluorouracil.
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
January 5, 2012
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| In: |
The New England journal of medicine
Year: 2012, Volume: 366, Issue: 1, Pages: 44-53 |
| ISSN: | 1533-4406 |
| DOI: | 10.1056/NEJMoa1009473 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1056/NEJMoa1009473 |
| Author Notes: | Matthias P.A. Ebert, Marc Tänzer, Benjamin Balluff, Elke Burgermeister, Antje Karen Kretzschmar, David J. Hughes, Reimo Tetzner, Catherine Lofton-Day, Robert Rosenberg, Anke C. Reinacher-Schick, Karsten Schulmann, Andrea Tannapfel, Ralf Hofheinz, Christoph Röcken, Gisela Keller, Rupert Langer, Katja Specht, Rainer Porschen, Jan Stöhlmacher-Williams, Tibor Schuster, Philipp Ströbel, Roland M. Schmid |
| Summary: | Patients whose tumors showed methylation and decreased expression of the gene TFAP2E were more than five times as likely as patients with normal TFAP2E gene expression to have resistance to fluorouracil. |
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| Item Description: | Gesehen am 16.04.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1533-4406 |
| DOI: | 10.1056/NEJMoa1009473 |