TFAP2E-DKK4 and chemoresistance in colorectal cancer: reply

Patients whose tumors showed methylation and decreased expression of the gene TFAP2E were more than five times as likely as patients with normal TFAP2E gene expression to have resistance to fluorouracil.

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Bibliographic Details
Main Authors: Ebert, Matthias (Author) , Burgermeister, Elke (Author) , Hofheinz, Ralf-Dieter (Author) , Ströbel, Philipp (Author)
Format: Article (Journal)
Language:English
Published: January 5, 2012
In: The New England journal of medicine
Year: 2012, Volume: 366, Issue: 1, Pages: 44-53
ISSN:1533-4406
DOI:10.1056/NEJMoa1009473
Online Access:Verlag, Volltext: https://doi.org/10.1056/NEJMoa1009473
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Author Notes:Matthias P.A. Ebert, Marc Tänzer, Benjamin Balluff, Elke Burgermeister, Antje Karen Kretzschmar, David J. Hughes, Reimo Tetzner, Catherine Lofton-Day, Robert Rosenberg, Anke C. Reinacher-Schick, Karsten Schulmann, Andrea Tannapfel, Ralf Hofheinz, Christoph Röcken, Gisela Keller, Rupert Langer, Katja Specht, Rainer Porschen, Jan Stöhlmacher-Williams, Tibor Schuster, Philipp Ströbel, Roland M. Schmid
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Summary:Patients whose tumors showed methylation and decreased expression of the gene TFAP2E were more than five times as likely as patients with normal TFAP2E gene expression to have resistance to fluorouracil.
Item Description:Gesehen am 16.04.2019
Physical Description:Online Resource
ISSN:1533-4406
DOI:10.1056/NEJMoa1009473