Time-to-first-event versus recurrent-event analysis: points to consider for selecting a meaningful analysis strategy in clinical trials with composite endpoints
Background Composite endpoints combining several event types of clinical interest often define the primary efficacy outcome in cardiologic trials. They are commonly evaluated as time-to-first-event,...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2018
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| In: |
Clinical research in cardiology
Year: 2018, Volume: 107, Issue: 5, Pages: 437-443 |
| ISSN: | 1861-0692 |
| DOI: | 10.1007/s00392-018-1205-7 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1007/s00392-018-1205-7 Verlag, Volltext: https://link.springer.com/article/10.1007/s00392-018-1205-7 
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| Author Notes: | Geraldine Rauch, Meinhard Kieser, Harald Binder, Antoni Bayes-Genis, Antje Jahn-Eimermacher |
| Summary: | Background Composite endpoints combining several event types of clinical interest often define the primary efficacy outcome in cardiologic trials. They are commonly evaluated as time-to-first-event,... |
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| Item Description: | Published online: 16 February 2018 Gesehen am 08.05.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1861-0692 |
| DOI: | 10.1007/s00392-018-1205-7 |