Time-to-first-event versus recurrent-event analysis: points to consider for selecting a meaningful analysis strategy in clinical trials with composite endpoints

Background Composite endpoints combining several event types of clinical interest often define the primary efficacy outcome in cardiologic trials. They are commonly evaluated as time-to-first-event,...

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Bibliographic Details
Main Authors: Rauch, Geraldine (Author) , Kieser, Meinhard (Author)
Format: Article (Journal)
Language:English
Published: 2018
In: Clinical research in cardiology
Year: 2018, Volume: 107, Issue: 5, Pages: 437-443
ISSN:1861-0692
DOI:10.1007/s00392-018-1205-7
Online Access:Verlag, Volltext: https://doi.org/10.1007/s00392-018-1205-7
Verlag, Volltext: https://link.springer.com/article/10.1007/s00392-018-1205-7
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Author Notes:Geraldine Rauch, Meinhard Kieser, Harald Binder, Antoni Bayes-Genis, Antje Jahn-Eimermacher

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