Quantitation of progenitor cell populations and growth factors after bone marrow aspirate concentration
The number of Mesenchymal Stem/Stromal Cells (MSCs) in the human bone marrow (BM) is small compared to other cell types. BM aspirate concentration (BMAC) may be used to increase numbers of MSCs, but the composition of MSC subpopulations and growth factors after processing are unknown. The purpose of...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
08 April 2019
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| In: |
Journal of translational medicine
Year: 2019, Volume: 17 |
| ISSN: | 1479-5876 |
| DOI: | 10.1186/s12967-019-1866-7 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1186/s12967-019-1866-7
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| Author Notes: | Richard Schäfer, Malcolm R. DeBaun, Erika Fleck, Christopher J. Centeno, Daniela Kraft, Johannes Leibacher, Karen Bieback, Erhard Seifried and Jason L. Dragoo |
| Summary: | The number of Mesenchymal Stem/Stromal Cells (MSCs) in the human bone marrow (BM) is small compared to other cell types. BM aspirate concentration (BMAC) may be used to increase numbers of MSCs, but the composition of MSC subpopulations and growth factors after processing are unknown. The purpose of this study was to assess the enrichment of stem/progenitor cells and growth factors in BM aspirate by two different commercial concentration devices versus standard BM aspiration. |
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| Item Description: | Gesehen am 13.05.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1479-5876 |
| DOI: | 10.1186/s12967-019-1866-7 |