Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex

Medial entorhinal cortex (MEC) is involved in memory processes that entail the replay of sequential firing of hippocampal place cells during rest periods and during behaviour. Here, the authors show that MEC lesioned animals show intact replay after an epoch of rats running on a linear track, while...

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Bibliographic Details
Main Authors: Chenani, Alireza (Author) , Schlesiger, Magdalene (Author)
Format: Article (Journal)
Language:English
Published: 22 March 2019
In: Nature Communications
Year: 2019, Volume: 10
ISSN:2041-1723
DOI:10.1038/s41467-019-09280-0
Online Access:Verlag, Volltext: https://doi.org/10.1038/s41467-019-09280-0
Verlag, Volltext: https://www.nature.com/articles/s41467-019-09280-0
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Author Notes:Alireza Chenani, Marta Sabariego, Magdalene I. Schlesiger, Jill K. Leutgeb, Stefan Leutgeb & Christian Leibold
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Summary:Medial entorhinal cortex (MEC) is involved in memory processes that entail the replay of sequential firing of hippocampal place cells during rest periods and during behaviour. Here, the authors show that MEC lesioned animals show intact replay after an epoch of rats running on a linear track, while replay during the behavioral epoch is reduced.
Item Description:Gesehen am 24.05.2019
Physical Description:Online Resource
ISSN:2041-1723
DOI:10.1038/s41467-019-09280-0