Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex

Medial entorhinal cortex (MEC) is involved in memory processes that entail the replay of sequential firing of hippocampal place cells during rest periods and during behaviour. Here, the authors show that MEC lesioned animals show intact replay after an epoch of rats running on a linear track, while...

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Hauptverfasser: Chenani, Alireza (VerfasserIn) , Schlesiger, Magdalene (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 22 March 2019
In: Nature Communications
Year: 2019, Jahrgang: 10
ISSN:2041-1723
DOI:10.1038/s41467-019-09280-0
Online-Zugang:Verlag, Volltext: https://doi.org/10.1038/s41467-019-09280-0
Verlag, Volltext: https://www.nature.com/articles/s41467-019-09280-0
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Verfasserangaben:Alireza Chenani, Marta Sabariego, Magdalene I. Schlesiger, Jill K. Leutgeb, Stefan Leutgeb & Christian Leibold
Beschreibung
Zusammenfassung:Medial entorhinal cortex (MEC) is involved in memory processes that entail the replay of sequential firing of hippocampal place cells during rest periods and during behaviour. Here, the authors show that MEC lesioned animals show intact replay after an epoch of rats running on a linear track, while replay during the behavioral epoch is reduced.
Beschreibung:Gesehen am 24.05.2019
Beschreibung:Online Resource
ISSN:2041-1723
DOI:10.1038/s41467-019-09280-0