Genome-wide methylation profiling and copy number analysis in atypical fibroxanthomas and pleomorphic dermal sarcomas indicate a similar molecular phenotype

Atypical fibroxanthomas (AFX) and pleomorphic dermal sarcomas (PDS) are lesions of the skin with overlapping histologic features and unspecific molecular traits. PDS behaves aggressive compared to AFX. Thus, a precise delineation, although challenging in some instances, is relevant.

Bibliographic Details

Main Authors:	Kölsche, Christian (Author) , Stichel, Damian (Author) , Griewank, Klaus G. (Author) , Schrimpf, Daniel (Author) , Reuss, David (Author) , Bewerunge-Hudler, Melanie (Author) , Vokuhl, Christian (Author) , Dinjens, Winand N. M. (Author) , Petersen, Iver (Author) , Mittelbronn, Michel (Author) , Cuevas-Bourdier, Adrian (Author) , Buslei, Rolf (Author) , Pfister, Stefan (Author) , Flucke, Uta (Author) , Mechtersheimer, Gunhild (Author) , Mentzel, Thomas (Author) , Deimling, Andreas von (Author)
Format:	Article (Journal)
Language:	English
Published:	14 February 2019
In:	Clinical Sarcoma Research Year: 2019, Volume: 9, Pages: 1-8
ISSN:	2045-3329
DOI:	10.1186/s13569-019-0113-6
Online Access:	Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13569-019-0113-6
Author Notes:	Christian Koelsche, Damian Stichel, Klaus G. Griewank, Daniel Schrimpf, David E. Reuss, Melanie Bewerunge-Hudler, Christian Vokuhl, Winand N. M. Dinjens, Iver Petersen, Michel Mittelbronn, Adrian Cuevas-Bourdier, Rolf Buslei, Stefan M. Pfister, Uta Flucke, Gunhild Mechtersheimer, Thomas Mentzel and Andreas von Deimling