A genetic screen pinpoints ribonucleotide reductase residues that sustain dNTP homeostasis and specifies a highly mutagenic type of dNTP imbalance

Abstract. The balance and the overall concentration of intracellular deoxyribonucleoside triphosphates (dNTPs) are important determinants of faithful DNA repli

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Bibliographic Details
Main Authors: Schmidt, Tobias Thomas (Author) , Wade, Rebecca C. (Author)
Format: Article (Journal)
Language:English
Published: [10 January 2019]
In: Nucleic acids research
Year: 2018, Volume: 47, Issue: 1, Pages: 237-252
ISSN:1362-4962
DOI:10.1093/nar/gky1154
Online Access:Verlag, Volltext: https://doi.org/10.1093/nar/gky1154
Verlag, Volltext: https://academic.oup.com/nar/article/47/1/237/5193336
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Author Notes:Tobias T. Schmidt, Sushma Sharma, Gloria X. Reyes, Kerstin Gries, Maike Gross, Boyu Zhao, Jui-Hung Yuan, Rebecca Wade, Andrei Chabes and Hans Hombauer
Description
Summary:Abstract. The balance and the overall concentration of intracellular deoxyribonucleoside triphosphates (dNTPs) are important determinants of faithful DNA repli
Item Description: Published: 20 November 2018
Gesehen am 21.06.2019
Physical Description:Online Resource
ISSN:1362-4962
DOI:10.1093/nar/gky1154