Advanced treatment planning

Treatment planning for protons and heavier ions is adapting technologies originally developed for photon dose optimization, but also has to meet its particular challenges. Since the quality of the applied dose is more sensitive to geometric uncertainties, treatment plan robust optimization has a muc...

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Bibliographic Details
Main Authors: Wedenberg, Minna (Author) , Mairani, Andrea (Author) , Alber, Markus (Author)
Format: Article (Journal)
Language:English
Published: 13 November 2018
In: Medical physics
Year: 2018, Volume: 45, Issue: 11, Pages: 1011-1023
ISSN:2473-4209
DOI:10.1002/mp.12943
Online Access:Verlag, Volltext: http://dx.doi.org/10.1002/mp.12943
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Author Notes:Minna Wedenberg, Chris Beltran, Andrea Mairani, Markus Alber
Description
Summary:Treatment planning for protons and heavier ions is adapting technologies originally developed for photon dose optimization, but also has to meet its particular challenges. Since the quality of the applied dose is more sensitive to geometric uncertainties, treatment plan robust optimization has a much more prominent role in particle therapy. This has led to specific planning tools, approaches, and research into new formulations of the robust optimization problems. Tools for solution space navigation and automatic planning are also being adapted to particle therapy. These challenges become even greater when detailed models of relative biological effectiveness (RBE) are included into dose optimization, as is required for heavier ions.
Item Description:Gesehen am 01.07.2019
Physical Description:Online Resource
ISSN:2473-4209
DOI:10.1002/mp.12943