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Patients with idiopathic recurrent miscarriage have abnormally high TGFß+ blood NK, NKT and T cells in the presence of abnormally low TGFß plasma levels

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Previously, we demonstrated up-regulated activated CD4+ and CD8+ T lymphocytes as well as up-regulated cytotoxic NK cells in the blood of patients with idiopathic recurrent miscarriage. In the present study, we tried to identify deficiencies in counter-regulating immune mechanisms of these patients.

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Bibliographic Details
Main Authors: Zhu, Li (Author) , Kuon, Ruben-Jeremias (Author) , Morath, Christian (Author) , Ekpoom, Naruemol (Author) , Daniel, Volker (Author)
Format: Article (Journal)
Language:English
Published: 4 March 2019
In: BMC immunology
Year: 2019, Volume: 20
ISSN:1471-2172
DOI:10.1186/s12865-019-0290-3
Online Access:Verlag, Volltext: https://doi.org/10.1186/s12865-019-0290-3
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Author Notes:Li Zhu, Mostafa Aly, Ruben Jeremias Kuon, Bettina Toth, Haihao Wang, Hristos Karakizlis, Rolf Weimer, Christian Morath, Eman Ibrahim, Naruemol Ekpoom, Gerhard Opelz and Volker Daniel
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Summary:Previously, we demonstrated up-regulated activated CD4+ and CD8+ T lymphocytes as well as up-regulated cytotoxic NK cells in the blood of patients with idiopathic recurrent miscarriage. In the present study, we tried to identify deficiencies in counter-regulating immune mechanisms of these patients.
Item Description:Gesehen am 15.07.2019
Physical Description:Online Resource
ISSN:1471-2172
DOI:10.1186/s12865-019-0290-3

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