Patients with idiopathic recurrent miscarriage have abnormally high TGFß+ blood NK, NKT and T cells in the presence of abnormally low TGFß plasma levels
Previously, we demonstrated up-regulated activated CD4+ and CD8+ T lymphocytes as well as up-regulated cytotoxic NK cells in the blood of patients with idiopathic recurrent miscarriage. In the present study, we tried to identify deficiencies in counter-regulating immune mechanisms of these patients.
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| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
4 March 2019
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| In: |
BMC immunology
Year: 2019, Jahrgang: 20 |
| ISSN: | 1471-2172 |
| DOI: | 10.1186/s12865-019-0290-3 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1186/s12865-019-0290-3
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| Verfasserangaben: | Li Zhu, Mostafa Aly, Ruben Jeremias Kuon, Bettina Toth, Haihao Wang, Hristos Karakizlis, Rolf Weimer, Christian Morath, Eman Ibrahim, Naruemol Ekpoom, Gerhard Opelz and Volker Daniel |
| Zusammenfassung: | Previously, we demonstrated up-regulated activated CD4+ and CD8+ T lymphocytes as well as up-regulated cytotoxic NK cells in the blood of patients with idiopathic recurrent miscarriage. In the present study, we tried to identify deficiencies in counter-regulating immune mechanisms of these patients. |
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| Beschreibung: | Gesehen am 15.07.2019 |
| Beschreibung: | Online Resource |
| ISSN: | 1471-2172 |
| DOI: | 10.1186/s12865-019-0290-3 |