DNA methylation, transcriptome and genetic copy number signatures of diffuse cerebral WHO grade II/III gliomas resolve cancer heterogeneity and development
Diffuse lower WHO grade II and III gliomas (LGG) are slowly progressing brain tumors, many of which eventually transform into a more aggressive type. LGG is characterized by widespread genetic and transcriptional heterogeneity, yet little is known about the heterogeneity of the DNA methylome, its fu...
Gespeichert in:
| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
25 April 2019
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| In: |
Acta Neuropathologica Communications
Year: 2019, Jahrgang: 7, Pages: 1-18 |
| ISSN: | 2051-5960 |
| DOI: | 10.1186/s40478-019-0704-8 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1186/s40478-019-0704-8
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| Verfasserangaben: | H. Binder, E. Willscher, H. Loeffler-Wirth, L. Hopp, D.T.W. Jones, S.M. Pfister, M. Kreuz, D. Gramatzki, E. Fortenbacher, B. Hentschel, M. Tatagiba, U. Herrlinger, H. Vatter, J. Matschke, M. Westphal, D. Krex, G. Schackert, J.C. Tonn, U. Schlegel, H.-J. Steiger, W. Wick, R. Weber, M. Weller, and M. Loeffler |
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DNA methylation, transcriptome and genetic copy number signatures of diffuse cerebral WHO grade II/III gliomas resolve cancer heterogeneity and development
BioMed Central 09 Jul. 2019 Universitätsbibliothek Heidelberg 09 Jul. 2019
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