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External validation of molecular subtype classifications of colorectal cancer based on microsatellite instability, CIMP, BRAF and KRAS

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Competing molecular classification systems have been proposed to complement the TNM staging system for a better prediction of survival in colorectal cancer (CRC). However, validation studies are so far lacking. The aim of this study was to validate and extend previously published molecular classific...

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Main Authors: Alwers, Elizabeth (Author) , Bläker, Hendrik (Author) , Walter, Viola (Author) , Jansen, Lina (Author) , Kloor, Matthias (Author) , Arnold, Alexander (Author) , Sieber-Frank, Julia (Author) , Herpel, Esther (Author) , Tagscherer, Katrin (Author) , Roth, Wilfried (Author) , Chang-Claude, Jenny (Author) , Brenner, Hermann (Author) , Hoffmeister, Michael (Author)
Format: Article (Journal)
Language:English
Published: 11 July 2019
In: BMC cancer
Year: 2019, Volume: 19, Pages: 1-10
ISSN:1471-2407
DOI:10.1186/s12885-019-5842-7
Online Access:Verlag, Volltext: https://doi.org/10.1186/s12885-019-5842-7
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Author Notes:Elizabeth Alwers, Hendrik Bläker, Viola Walter, Lina Jansen, Matthias Kloor, Alexander Arnold, Julia Sieber-Frank, Esther Herpel, Katrin E. Tagscherer, Wilfried Roth, Jenny Chang-Claude, Hermann Brenner, and Michael Hoffmeister
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Summary:Competing molecular classification systems have been proposed to complement the TNM staging system for a better prediction of survival in colorectal cancer (CRC). However, validation studies are so far lacking. The aim of this study was to validate and extend previously published molecular classifications of CRC in a large independent cohort of CRC patients.
Item Description:Gesehen am 19.07.2019
Physical Description:Online Resource
ISSN:1471-2407
DOI:10.1186/s12885-019-5842-7

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