Sweaty feet in adolescents: early use of botulinum type A toxin in juvenile plantar hyperhidrosis
Background/Objectives Plantar hyperhidrosis can have severe social effects on children and adolescents. Therapeutic options include antiperspirants and surgical interventions (eg, sympathectomy). Botulinum type A toxin is approved for axillary hyperhidrosis in adults only. The aim of the study was t...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
04 September 2018
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| In: |
Pediatric dermatology
Year: 2018, Volume: 35, Issue: 6, Pages: 784-786 |
| ISSN: | 1525-1470 |
| DOI: | 10.1111/pde.13628 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1111/pde.13628 Verlag, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/pde.13628 
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| Author Notes: | Matthias K. Bernhard, Matthias Krause, Steffen Syrbe |
| Summary: | Background/Objectives Plantar hyperhidrosis can have severe social effects on children and adolescents. Therapeutic options include antiperspirants and surgical interventions (eg, sympathectomy). Botulinum type A toxin is approved for axillary hyperhidrosis in adults only. The aim of the study was the determination of effect and safety of botulinum type A toxin in plantar hyperhidrosis in juvenile patients. Methods Children and adolescents with idiopathic focal plantar hyperhidrosis were treated with 50-100 U of botulinum type A toxin per sole. Local anesthesia was provided using topical eutectic mixture of local anesthetics cream and ice, in combination with midazolam as an anxiolytic. Results Fifteen patients (aged 12-17) were included in the study. Best results were achieved with a dose of 75-100 U of botulinum type A toxin per sole. Two patients did not benefit from the therapy, and 11 (73%) were satisfied with the results. Nine patients (60%) experienced pain at the injection site for a maximum duration of 3 days. One patient reported transient focal weakness for 4 weeks. Conclusion Botulinum type A toxin seems to be a safe secondary treatment option for plantar hyperhidrosis in adolescents aged 12 and older. A dose of 75-100 U per sole resulted in a good therapeutic effect of variable duration in most patients. There were no severe side effects. |
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| Item Description: | Gesehen am 31.07.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1525-1470 |
| DOI: | 10.1111/pde.13628 |