Robust near real-time estimation of physiological parameters from megapixel multispectral images with inverse Monte Carlo and random forest regression

PurposeMultispectral imaging can provide reflectance measurements at multiple spectral bands for each image pixel. These measurements can be used for estimation of important physiological parameters, such as oxygenation, which can provide indicators for the success of surgical treatment or the prese...

Full description

Saved in:
Bibliographic Details
Main Authors: Wirkert, Sebastian (Author) , Kenngott, Hannes Götz (Author) , Mayer, Benjamin (Author) , Mietkowski, Patrick (Author) , Wagner, Martin (Author) , Sauer, Peter (Author)
Format: Article (Journal)
Language:English
Published: 3 May 2016
In: International journal of computer assisted radiology and surgery
Year: 2016, Volume: 11, Issue: 6, Pages: 909-917
ISSN:1861-6429
DOI:10.1007/s11548-016-1376-5
Online Access:Verlag, Volltext: https://doi.org/10.1007/s11548-016-1376-5
Get full text
Author Notes:Sebastian J. Wirkert, Hannes Kenngott, Benjamin Mayer, Patrick Mietkowski, Martin Wagner, Peter Sauer, Neil T. Clancy, Daniel S. Elson, Lena Maier-Hein
Description
Summary:PurposeMultispectral imaging can provide reflectance measurements at multiple spectral bands for each image pixel. These measurements can be used for estimation of important physiological parameters, such as oxygenation, which can provide indicators for the success of surgical treatment or the presence of abnormal tissue. The goal of this work was to develop a method to estimate physiological parameters in an accurate and rapid manner suited for modern high-resolution laparoscopic images.MethodsWhile previous methods for oxygenation estimation are based on either simple linear methods or complex model-based approaches exclusively suited for off-line processing, we propose a new approach that combines the high accuracy of model-based approaches with the speed and robustness of modern machine learning methods. Our concept is based on training random forest regressors using reflectance spectra generated with Monte Carlo simulations.ResultsAccording to extensive in silico and in vivo experiments, the method features higher accuracy and robustness than state-of-the-art online methods and is orders of magnitude faster than other nonlinear regression based methods.ConclusionOur current implementation allows for near real-time oxygenation estimation from megapixel multispectral images and is thus well suited for online tissue analysis.
Item Description:Gesehen am 13.08.2019
Physical Description:Online Resource
ISSN:1861-6429
DOI:10.1007/s11548-016-1376-5