Immunotherapy of melanoma

Arising from melanocytes in skin, mucosal membranes, eye, and meninges, melanoma is a tumor that has been associated with poor prognosis in advanced disease stages. Given the poor response to chemotherapy and radiation therapy, new treatment approaches with targeted therapy, immunotherapy, and adopt...

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Bibliographic Details
Main Authors: Bender, Carolin (Author) , Hassel, Jessica C. (Author) , Enk, Alexander (Author)
Format: Article (Journal)
Language:English
Published: May 25, 2016
In: Oncology research and treatment
Year: 2016, Volume: 39, Issue: 6, Pages: 369-376
ISSN:2296-5262
DOI:10.1159/000446716
Online Access:Verlag, Volltext: https://doi.org/10.1159/000446716
Verlag, Volltext: https://www.karger.com/Article/FullText/446716
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Author Notes:Carolin Bender, Jessica C. Hassel, Alexander Enk
Description
Summary:Arising from melanocytes in skin, mucosal membranes, eye, and meninges, melanoma is a tumor that has been associated with poor prognosis in advanced disease stages. Given the poor response to chemotherapy and radiation therapy, new treatment approaches with targeted therapy, immunotherapy, and adoptive T-cell therapy have revolutionized the standard of care for patients with advanced melanoma. This review provides a short overview of past, present, and future immunotherapeutic approaches and their limitations, with a focus on new combination agents in early clinical trials.
Item Description:Gesehen am 16.08.2019
Physical Description:Online Resource
ISSN:2296-5262
DOI:10.1159/000446716