Architecture of a mammalian glomerular domain revealed by novel volume electroporation using nanoengineered microelectrodes

Microcircuit tracing reconstructions often rely on statistical labeling that may not detect all inputs and outputs of a microcircuit. Here the authors employ a novel electroporation approach to densely label neurons and demonstrate its ability to identify sparse anatomical features in the olfactory...

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Main Authors: Schwarz, Daniel (Author) , Bosch, C. (Author) , Feinauer, C. (Author) , Whiteley, I. (Author) , Margrie, T. W. (Author) , Cutforth, T. (Author) , Schaefer, Andreas T. (Author)
Format: Article (Journal)
Language:English
Published: 12 January 2018
In: Nature Communications
Year: 2018, Volume: 9
ISSN:2041-1723
DOI:10.1038/s41467-017-02560-7
Online Access:Verlag, Volltext: https://doi.org/10.1038/s41467-017-02560-7
Verlag, Volltext: https://www.nature.com/articles/s41467-017-02560-7
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Author Notes:D. Schwarz, M. Kollo, C. Bosch, C. Feinauer, I. Whiteley, T.W. Margrie, T. Cutforth & A.T. Schaefer
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Summary:Microcircuit tracing reconstructions often rely on statistical labeling that may not detect all inputs and outputs of a microcircuit. Here the authors employ a novel electroporation approach to densely label neurons and demonstrate its ability to identify sparse anatomical features in the olfactory glomerulus.
Item Description:Gesehen am 03.09.2019
Physical Description:Online Resource
ISSN:2041-1723
DOI:10.1038/s41467-017-02560-7