Innate immune response in implant-associated infections: neutrophils against biofilms

Biofilm has been recognized as a well-protected form of living for bacteria, contributing to bacterial pathogenicity, particularly for opportunistic species. Biofilm-associated infections are marked by their persistence. Extensive research has been devoted to the formation and composition of biofilm...

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Bibliographic Details
Main Authors: Dapunt, Ulrike A. (Author) , Hänsch, Gertrud Maria (Author) , Arciola, Carla Renata (Author)
Format: Article (Journal)
Language:English
Published: 18 May 2016
In: Materials
Year: 2016, Volume: 9, Issue: 5
ISSN:1996-1944
DOI:10.3390/ma9050387
Online Access:Verlag, Volltext: https://doi.org/10.3390/ma9050387
Verlag, Volltext: https://www.mdpi.com/1996-1944/9/5/387
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Author Notes:Ulrike Dapunt, Gertrud Maria Hänsch and Carla Renata Arciola
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Summary:Biofilm has been recognized as a well-protected form of living for bacteria, contributing to bacterial pathogenicity, particularly for opportunistic species. Biofilm-associated infections are marked by their persistence. Extensive research has been devoted to the formation and composition of biofilms. The immune response against biofilms remains rather unexplored, but there is the notion that bacteria within a biofilm are protected from host defences. Here we glance at the mechanisms by which neutrophils recognize and face biofilms in implant infections and discuss the implications of this interplay, as well as speculate on its significance.
Item Description:Gesehen am 16.09.2019
Physical Description:Online Resource
ISSN:1996-1944
DOI:10.3390/ma9050387