Cover Image

AAV vector-mediated in vivo reprogramming into pluripotency

In vivo reprogramming of somatic cells is hampered by the need for vectors to express the OKSM factors in selected organs. Here the authors report new AAV-based vectors capable of in vivo reprogramming at low doses.

Saved in:
Bibliographic Details
Main Authors: Senís Herrero, Elena (Author) , Mosteiro, Lluc (Author) , Wilkening, Stefan (Author) , Wiedtke, Ellen (Author) , Nowrouzi, Ali (Author) , Afzal, Saira (Author) , Fronza, Raffaele (Author) , Landerer, Henrik (Author) , Abad, Maria (Author) , Niopek, Dominik (Author) , Schmidt, Manfred (Author) , Serrano, Manuel (Author) , Grimm, Dirk (Author)
Format: Article (Journal)
Language:English
Published: 09 July 2018
In: Nature Communications
Year: 2018, Volume: 9
ISSN:2041-1723
DOI:10.1038/s41467-018-05059-x
Online Access:Verlag, Volltext: https://doi.org/10.1038/s41467-018-05059-x
Verlag, Volltext: https://www.nature.com/articles/s41467-018-05059-x
Get full text
Author Notes:Elena Senís, Lluc Mosteiro, Stefan Wilkening, Ellen Wiedtke, Ali Nowrouzi, Saira Afzal, Raffaele Fronza, Henrik Landerer, Maria Abad, Dominik Niopek, Manfred Schmidt, Manuel Serrano & Dirk Grimm

MARC

LEADER 00000caa a2200000 c 4500
001 1677713453
003 DE-627
005 20230428021834.0
007 cr uuu---uuuuu
008 190925s2018 xx |||||o 00| ||eng c
024 7 |a 10.1038/s41467-018-05059-x  |2 doi 
035 |a (DE-627)1677713453 
035 |a (DE-599)KXP1677713453 
035 |a (OCoLC)1341244483 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 32  |2 sdnb 
100 1 |a Senís Herrero, Elena  |e VerfasserIn  |0 (DE-588)1080250026  |0 (DE-627)844088617  |0 (DE-576)453431690  |4 aut 
245 1 0 |a AAV vector-mediated in vivo reprogramming into pluripotency  |c Elena Senís, Lluc Mosteiro, Stefan Wilkening, Ellen Wiedtke, Ali Nowrouzi, Saira Afzal, Raffaele Fronza, Henrik Landerer, Maria Abad, Dominik Niopek, Manfred Schmidt, Manuel Serrano & Dirk Grimm 
264 1 |c 09 July 2018 
300 |a 14 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 25.09.2019 
520 |a In vivo reprogramming of somatic cells is hampered by the need for vectors to express the OKSM factors in selected organs. Here the authors report new AAV-based vectors capable of in vivo reprogramming at low doses. 
700 1 |a Mosteiro, Lluc  |e VerfasserIn  |4 aut 
700 1 |a Wilkening, Stefan  |d 1972-  |e VerfasserIn  |0 (DE-588)128424818  |0 (DE-627)706983203  |0 (DE-576)297137131  |4 aut 
700 1 |a Wiedtke, Ellen  |e VerfasserIn  |0 (DE-588)1071738372  |0 (DE-627)826301347  |0 (DE-576)433285206  |4 aut 
700 1 |a Nowrouzi, Ali  |d 1976-  |e VerfasserIn  |0 (DE-588)133683664  |0 (DE-627)551102225  |0 (DE-576)300023383  |4 aut 
700 1 |a Afzal, Saira  |e VerfasserIn  |0 (DE-588)112918417X  |0 (DE-627)883816210  |0 (DE-576)486243664  |4 aut 
700 1 |a Fronza, Raffaele  |e VerfasserIn  |0 (DE-588)1048496406  |0 (DE-627)780549414  |0 (DE-576)40232935X  |4 aut 
700 1 |a Landerer, Henrik  |e VerfasserIn  |4 aut 
700 1 |a Abad, Maria  |e VerfasserIn  |4 aut 
700 1 |a Niopek, Dominik  |e VerfasserIn  |0 (DE-588)107173685X  |0 (DE-627)826298109  |0 (DE-576)433282479  |4 aut 
700 1 |a Schmidt, Manfred  |d 1967-2022  |e VerfasserIn  |0 (DE-588)122922301  |0 (DE-627)706092430  |0 (DE-576)293477620  |4 aut 
700 1 |a Serrano, Manuel  |e VerfasserIn  |4 aut 
700 1 |a Grimm, Dirk  |e VerfasserIn  |0 (DE-588)1016476671  |0 (DE-627)70553376X  |0 (DE-576)352260645  |4 aut 
773 0 8 |i Enthalten in  |t Nature Communications  |d [London] : Springer Nature, 2010  |g 9(2018) Article number: 2651, 14 Seiten  |h Online-Ressource  |w (DE-627)626457688  |w (DE-600)2553671-0  |w (DE-576)331555905  |x 2041-1723  |7 nnas  |a AAV vector-mediated in vivo reprogramming into pluripotency 
773 1 8 |g volume:9  |g year:2018  |g extent:14  |a AAV vector-mediated in vivo reprogramming into pluripotency 
856 4 0 |u https://doi.org/10.1038/s41467-018-05059-x  |x Verlag  |x Resolving-System  |3 Volltext 
856 4 0 |u https://www.nature.com/articles/s41467-018-05059-x  |x Verlag  |3 Volltext 
951 |a AR 
992 |a 20190925 
993 |a Article 
994 |a 2018 
998 |g 1016476671  |a Grimm, Dirk  |m 1016476671:Grimm, Dirk  |d 910000  |d 911700  |e 910000PG1016476671  |e 911700PG1016476671  |k 0/910000/  |k 1/910000/911700/  |p 12 
998 |g 122922301  |a Schmidt, Manfred  |m 122922301:Schmidt, Manfred  |d 140000  |e 140000PS122922301  |k 0/140000/  |p 11 
998 |g 107173685X  |a Niopek, Dominik  |m 107173685X:Niopek, Dominik  |d 700000  |d 716000  |d 160000  |d 160100  |e 700000PN107173685X  |e 716000PN107173685X  |e 160000PN107173685X  |e 160100PN107173685X  |k 0/700000/  |k 1/700000/716000/  |k 0/160000/  |k 1/160000/160100/  |p 10 
998 |g 112918417X  |a Afzal, Saira  |m 112918417X:Afzal, Saira  |d 910000  |e 910000PA112918417X  |k 0/910000/  |p 6 
998 |g 133683664  |a Nowrouzi, Ali  |m 133683664:Nowrouzi, Ali  |d 910000  |d 911400  |e 910000PN133683664  |e 911400PN133683664  |k 0/910000/  |k 1/910000/911400/  |p 5 
998 |g 1071738372  |a Wiedtke, Ellen  |m 1071738372:Wiedtke, Ellen  |d 700000  |d 716000  |e 700000PW1071738372  |e 716000PW1071738372  |k 0/700000/  |k 1/700000/716000/  |p 4 
998 |g 128424818  |a Wilkening, Stefan  |m 128424818:Wilkening, Stefan  |d 910000  |e 910000PW128424818  |k 0/910000/  |p 3 
998 |g 1080250026  |a Senís Herrero, Elena  |m 1080250026:Senís Herrero, Elena  |d 910000  |d 911700  |e 910000PS1080250026  |e 911700PS1080250026  |k 0/910000/  |k 1/910000/911700/  |p 1  |x j 
999 |a KXP-PPN1677713453  |e 3517915548 
BIB |a Y 
SER |a journal 
JSO |a {"origin":[{"dateIssuedDisp":"09 July 2018","dateIssuedKey":"2018"}],"name":{"displayForm":["Elena Senís, Lluc Mosteiro, Stefan Wilkening, Ellen Wiedtke, Ali Nowrouzi, Saira Afzal, Raffaele Fronza, Henrik Landerer, Maria Abad, Dominik Niopek, Manfred Schmidt, Manuel Serrano & Dirk Grimm"]},"person":[{"family":"Senís Herrero","given":"Elena","role":"aut","display":"Senís Herrero, Elena"},{"family":"Mosteiro","given":"Lluc","role":"aut","display":"Mosteiro, Lluc"},{"family":"Wilkening","given":"Stefan","role":"aut","display":"Wilkening, Stefan"},{"display":"Wiedtke, Ellen","role":"aut","given":"Ellen","family":"Wiedtke"},{"family":"Nowrouzi","given":"Ali","role":"aut","display":"Nowrouzi, Ali"},{"display":"Afzal, Saira","role":"aut","given":"Saira","family":"Afzal"},{"display":"Fronza, Raffaele","role":"aut","given":"Raffaele","family":"Fronza"},{"family":"Landerer","given":"Henrik","role":"aut","display":"Landerer, Henrik"},{"role":"aut","display":"Abad, Maria","family":"Abad","given":"Maria"},{"role":"aut","display":"Niopek, Dominik","family":"Niopek","given":"Dominik"},{"role":"aut","display":"Schmidt, Manfred","family":"Schmidt","given":"Manfred"},{"family":"Serrano","given":"Manuel","role":"aut","display":"Serrano, Manuel"},{"display":"Grimm, Dirk","role":"aut","family":"Grimm","given":"Dirk"}],"note":["Gesehen am 25.09.2019"],"recId":"1677713453","type":{"media":"Online-Ressource","bibl":"article-journal"},"relHost":[{"origin":[{"dateIssuedDisp":"[2010]-","publisherPlace":"[London] ; [London]","publisher":"Springer Nature ; Nature Publishing Group UK"}],"part":{"year":"2018","extent":"14","volume":"9","text":"9(2018) Article number: 2651, 14 Seiten"},"note":["Gesehen am 13.06.24"],"recId":"626457688","pubHistory":["2010-"],"disp":"AAV vector-mediated in vivo reprogramming into pluripotencyNature Communications","type":{"bibl":"periodical","media":"Online-Ressource"},"language":["eng"],"title":[{"title_sort":"Nature Communications","title":"Nature Communications"}],"id":{"eki":["626457688"],"zdb":["2553671-0"],"issn":["2041-1723"]},"physDesc":[{"extent":"Online-Ressource"}]}],"id":{"eki":["1677713453"],"doi":["10.1038/s41467-018-05059-x"]},"language":["eng"],"title":[{"title_sort":"AAV vector-mediated in vivo reprogramming into pluripotency","title":"AAV vector-mediated in vivo reprogramming into pluripotency"}],"physDesc":[{"extent":"14 S."}]} 
SRT |a SENISHERREAAVVECTORM0920 

Similar Items