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Severe human Bocavirus 1 respiratory tract infection in an immunodeficient child with fatal outcome

We report a case of lower respiratory tract infection with human bocavirus 1 (HboV1) in an immunodeficient 6-month-old boy leading to respiratory failure with fatal outcome. Polymerase chain reaction of serum/tracheal secretions revealed exceptionally high HboV1-DNA levels and immunoassays showed se...

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Bibliographic Details
Main Authors: Tabatabai, Julia (Author) , Fakhiri, Julia (Author) , Meyburg, Jochen (Author) , Linse, Kai-Philipp (Author) , Grimm, Dirk (Author) , Schnitzler, Paul (Author)
Format: Article (Journal)
Language:English
Published: September 2019
In: The pediatric infectious disease journal
Year: 2019, Volume: 38, Issue: 9, Pages: e219-e222
ISSN:1532-0987
DOI:10.1097/INF.0000000000002354
Online Access:Verlag, Volltext: https://doi.org/10.1097/INF.0000000000002354
Verlag: https://journals.lww.com/pidj/Abstract/2019/09000/Severe_Human_Bocavirus_1_Respiratory_Tract.22.aspx
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Author Notes:Julia Tabatabai, Julia Fakhiri, Jochen Meyburg, Kai-Philipp Linse, Man Xu, Maria Söderlund-Venermo, Dirk Grimm, Paul Schnitzler
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Summary:We report a case of lower respiratory tract infection with human bocavirus 1 (HboV1) in an immunodeficient 6-month-old boy leading to respiratory failure with fatal outcome. Polymerase chain reaction of serum/tracheal secretions revealed exceptionally high HboV1-DNA levels and immunoassays showed seroconversion indicating an acute primary HboV1 infection. All assays for other pathogens were negative, strongly suggesting that HboV1 was the causative agent in this case.
Item Description:Gesehen am 09.10.2019
Physical Description:Online Resource
ISSN:1532-0987
DOI:10.1097/INF.0000000000002354

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