Severe human Bocavirus 1 respiratory tract infection in an immunodeficient child with fatal outcome
We report a case of lower respiratory tract infection with human bocavirus 1 (HboV1) in an immunodeficient 6-month-old boy leading to respiratory failure with fatal outcome. Polymerase chain reaction of serum/tracheal secretions revealed exceptionally high HboV1-DNA levels and immunoassays showed se...
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| Hauptverfasser: | , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
September 2019
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| In: |
The pediatric infectious disease journal
Year: 2019, Jahrgang: 38, Heft: 9, Pages: e219-e222 |
| ISSN: | 1532-0987 |
| DOI: | 10.1097/INF.0000000000002354 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1097/INF.0000000000002354 Verlag: https://journals.lww.com/pidj/Abstract/2019/09000/Severe_Human_Bocavirus_1_Respiratory_Tract.22.aspx |
| Verfasserangaben: | Julia Tabatabai, Julia Fakhiri, Jochen Meyburg, Kai-Philipp Linse, Man Xu, Maria Söderlund-Venermo, Dirk Grimm, Paul Schnitzler |
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| 520 | |a We report a case of lower respiratory tract infection with human bocavirus 1 (HboV1) in an immunodeficient 6-month-old boy leading to respiratory failure with fatal outcome. Polymerase chain reaction of serum/tracheal secretions revealed exceptionally high HboV1-DNA levels and immunoassays showed seroconversion indicating an acute primary HboV1 infection. All assays for other pathogens were negative, strongly suggesting that HboV1 was the causative agent in this case. | ||
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