Assessing the lifetime cost-effectiveness of low-protein infant formula as early obesity prevention strategy: The CHOP Randomized Trial
Background: Although there is a growing number of early childhood obesity prevention programs, only a few of them are effective in the long run. Even fewer reports exist on lifetime cost-effectiveness of early prevention strategies. This paper aimed to assess the lifetime cost-effectiveness of infan...
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| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
19 July 2019
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| In: |
Nutrients
Year: 2019, Jahrgang: 11, Heft: 7 |
| ISSN: | 2072-6643 |
| DOI: | 10.3390/nu11071653 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.3390/nu11071653 Verlag, kostenfrei, Volltext: https://www.mdpi.com/2072-6643/11/7/1653 
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| Verfasserangaben: | Diana Sonntag, Freia De Bock, Martina Totzauer and Berthold Koletzko |
| Zusammenfassung: | Background: Although there is a growing number of early childhood obesity prevention programs, only a few of them are effective in the long run. Even fewer reports exist on lifetime cost-effectiveness of early prevention strategies. This paper aimed to assess the lifetime cost-effectiveness of infant feeding modification aiming at reducing risk of later obesity. Methods: The simulation model consists of two parts: (a) Model I used data from the European Childhood Obesity Project (CHOP) trial (up to 6 years) and the German Interview and Examination Survey for Children (KiGGS) (6-17 years) to evaluate BMI trajectories of infants receiving either lower protein (LP) or higher protein (HP) content formula; and (b) Model II estimated lifetime cost-effectiveness based on Model I BMI trajectories. Compared to HP formula, LP formula feeding would incur lower costs that are attributable to childhood obesity across all decades of life. Results: Our analysis showed that LP formula would be cost-effective in terms of a positive net monetary benefit (discounted 3%) as an obesity prevention strategy. For the 19% of infants fed with formula in Germany, the LP strategy would result in cost savings of € 2.5 billion. Conclusions: Our study is one of the first efforts to provide much-needed cost-effectiveness evidence of infant feeding modification, thereby potentially motivating interventionists to reassess their resource allocation. |
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| Beschreibung: | Gesehen am 17.10.2019 |
| Beschreibung: | Online Resource |
| ISSN: | 2072-6643 |
| DOI: | 10.3390/nu11071653 |