Gadolinium leakage in ocular structures in optic neuritis
Background - We investigated the frequency of blood-retina barrier impairment in optic neuritis (ON) using gadolinium leakage in ocular structures (GLOS), a novel imaging marker on contrast enhanced fluid attenuated inversion recovery images (FLAIR). - Methods - In 12 patients with acute ON who unde...
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
October 2019
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| In: |
Journal of clinical neuroscience
Year: 2019, Volume: 68, Pages: 268-270 |
| ISSN: | 1532-2653 |
| DOI: | 10.1016/j.jocn.2019.05.050 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1016/j.jocn.2019.05.050 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0967586819304771 
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| Author Notes: | Alex Förster, Johannes Böhme, Christoph Groden, Holger Wenz |
| Summary: | Background - We investigated the frequency of blood-retina barrier impairment in optic neuritis (ON) using gadolinium leakage in ocular structures (GLOS), a novel imaging marker on contrast enhanced fluid attenuated inversion recovery images (FLAIR). - Methods - In 12 patients with acute ON who underwent repeated MRI the presence of GLOS was noted on contrast-enhanced FLAIR. - Results - Bilateral GLOS was observed in 4 (33.3%): in 3 symmetrical, and in 1 asymmetrical. In the latter GLOS was ipsilateral to the ON. - Conclusions - GLOS may be observed frequently in ON. Asymmetrical GLOS may be caused by a more local effect of ON. |
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| Item Description: | Gesehen am 18.10.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1532-2653 |
| DOI: | 10.1016/j.jocn.2019.05.050 |