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Extending the time window for intravenous thrombolysis in acute ischemic stroke using magnetic resonance imaging-based patient selection

Background: Intravenous thrombolysis with alteplase within a time window up to 4.5 h is the only approved pharmacological treatment for acute ischemic stroke. We studied whether acute ischemic stroke patients with penumbral tissue identified on magnetic resonance imaging 4.5-9 h after symptom onset...

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Hauptverfasser: Ringleb, Peter A. (VerfasserIn) , Bendszus, Martin (VerfasserIn) , Fatar, Marc (VerfasserIn) , Hacke, Werner (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: April 4, 2019
In: International journal of stroke
Year: 2019, Jahrgang: 14, Heft: 5, Pages: 483-490
ISSN:1747-4949
DOI:10.1177/1747493019840938
Online-Zugang:Verlag, Volltext: https://doi.org/10.1177/1747493019840938
Verlag: http://journals.sagepub.com/doi/10.1177/1747493019840938
Volltext
Verfasserangaben:Peter Ringleb, Martin Bendszus, Erich Bluhmki, Geoffrey Donnan, Christoph Eschenfelder, Marc Fatar, Christof Kessler, Carlos Molina, Didier Leys, Girish Muddegowda, Sven Poli, Peter Schellinger, Stefan Schwab, Joaquin Serena, Danilo Toni, Nils Wahlgren and Werner Hacke, for the ECASS-4 study group
Beschreibung
Zusammenfassung:Background: Intravenous thrombolysis with alteplase within a time window up to 4.5 h is the only approved pharmacological treatment for acute ischemic stroke. We studied whether acute ischemic stroke patients with penumbral tissue identified on magnetic resonance imaging 4.5-9 h after symptom onset benefit from intravenous thrombolysis compared to placebo.
Beschreibung:Gesehen am 21.10.2019
Beschreibung:Online Resource
ISSN:1747-4949
DOI:10.1177/1747493019840938

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