A rare cause for lower back pain: a case of an IgG4-related periaortitis
IgG4-related disease (IgG4-RD) are a group of autoinflammatory diseases often presenting as tumor-like lesions because of their infiltrative or mass forming behavior. They are characterized by a typical histology consisting of storiform fibrosis, high numbers of infiltrating IgG4-positive plasma cel...
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| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2016
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| In: |
Clinical rheumatology
Year: 2016, Volume: 35, Issue: 1, Pages: 265-270 |
| ISSN: | 1434-9949 |
| DOI: | 10.1007/s10067-014-2535-0 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1007/s10067-014-2535-0
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| Author Notes: | Christian Löffler, Johannes Hoffend, Martin Rebel, Rüdiger Waldherr, Michael Uppenkamp, Raoul Bergner |
| Summary: | IgG4-related disease (IgG4-RD) are a group of autoinflammatory diseases often presenting as tumor-like lesions because of their infiltrative or mass forming behavior. They are characterized by a typical histology consisting of storiform fibrosis, high numbers of infiltrating IgG4-positive plasma cells, obliterative phlebitis, and a moderate presence of eosinophilic cells. Serum IgG4 levels can be elevated. We present a case of a 57 year-old male patient with immobilizing lower back pain, fever, and night sweats. We diagnosed IgG4-related periaortitis using serum IgG4 levels, abdominal ultrasound, PET/CT, and histology. We successfully treated the patient with glucocorticoids (GC) and azathioprine. Periaortitis is a rare presentation of IgG4-RD and therefore noteworthy. It has to be considered in patients with a retroperitoneal mass. |
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| Item Description: | Gesehen am 21.10.2019 Published online: 23 February 2014 |
| Physical Description: | Online Resource |
| ISSN: | 1434-9949 |
| DOI: | 10.1007/s10067-014-2535-0 |