Premature mortality in autism spectrum disorder
Background - Mortality has been suggested to be increased in autism spectrum disorder - (ASD). Aims - To examine both all-cause and cause-specific mortality in ASD, as well as - investigate moderating role of gender and intellectual ability. Method - Odds ratios (ORs) were calculated for a populatio...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2016
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| In: |
The British journal of psychiatry
Year: 2016, Volume: 208, Issue: 3, Pages: 232-238 |
| ISSN: | 1472-1465 |
| DOI: | 10.1192/bjp.bp.114.160192 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1192/bjp.bp.114.160192 Verlag, Volltext: https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/premature-mortality-in-autism-spectrum-disorder/4C9260DB64DFC29AF945D32D1C15E8F2 
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| Author Notes: | Tatja Hirvikoski, Ellenor Mittendorfer-Rutz, Marcus Boman, Henrik Larsson, Paul Lichtenstein and Sven Bölte |
| Summary: | Background - Mortality has been suggested to be increased in autism spectrum disorder - (ASD). Aims - To examine both all-cause and cause-specific mortality in ASD, as well as - investigate moderating role of gender and intellectual ability. Method - Odds ratios (ORs) were calculated for a population-based cohort of ASD - probands (n = 27 122, diagnosed between 1987 and 2009) - compared with gender-, age- and county of residence-matched controls - (n = 2 672 185). Results - During the observed period, 24 358 (0.91%) individuals in the general - population died, whereas the corresponding figure for individuals with - ASD was 706 (2.60%; OR = 2.56; 95% CI 2.38-2.76). Cause-specific analyses - showed elevated mortality in ASD for almost all analysed diagnostic - categories. Mortality and patterns for cause-specific mortality were - partly moderated by gender and general intellectual ability. Conclusions - Premature mortality was markedly increased in ASD owing to a multitude of - medical conditions. |
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| Item Description: | Gesehen am 24.10.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1472-1465 |
| DOI: | 10.1192/bjp.bp.114.160192 |