Sticking around: short-range activity of Wnt ligands

Wnt ligands are secreted lipid-modified proteins that are essential for development and homeostasis. Published recently in Nature, Farin et al. (2016) report that Wnt3 acts at a short distance during growth of mouse intestinal organoids, suggesting that Wnt proteins remain membrane-bound to activate...

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Bibliographic Details
Main Authors: Boutros, Michael (Author) , Niehrs, Christof (Author)
Format: Article (Journal)
Language:English
Published: March 7, 2016
In: Developmental cell
Year: 2016, Volume: 36, Issue: 5, Pages: 485-486
ISSN:1878-1551
DOI:10.1016/j.devcel.2016.02.018
Online Access:Verlag, Volltext: https://doi.org/10.1016/j.devcel.2016.02.018
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S1534580716300739
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Author Notes:Michael Boutros and Christof Niehrs
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Summary:Wnt ligands are secreted lipid-modified proteins that are essential for development and homeostasis. Published recently in Nature, Farin et al. (2016) report that Wnt3 acts at a short distance during growth of mouse intestinal organoids, suggesting that Wnt proteins remain membrane-bound to activate signaling at a short range from their source.
Item Description:Gesehen am 31.10.2019
Physical Description:Online Resource
ISSN:1878-1551
DOI:10.1016/j.devcel.2016.02.018