Sticking around: short-range activity of Wnt ligands
Wnt ligands are secreted lipid-modified proteins that are essential for development and homeostasis. Published recently in Nature, Farin et al. (2016) report that Wnt3 acts at a short distance during growth of mouse intestinal organoids, suggesting that Wnt proteins remain membrane-bound to activate...
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
March 7, 2016
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| In: |
Developmental cell
Year: 2016, Jahrgang: 36, Heft: 5, Pages: 485-486 |
| ISSN: | 1878-1551 |
| DOI: | 10.1016/j.devcel.2016.02.018 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1016/j.devcel.2016.02.018 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S1534580716300739 
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| Verfasserangaben: | Michael Boutros and Christof Niehrs |
| Zusammenfassung: | Wnt ligands are secreted lipid-modified proteins that are essential for development and homeostasis. Published recently in Nature, Farin et al. (2016) report that Wnt3 acts at a short distance during growth of mouse intestinal organoids, suggesting that Wnt proteins remain membrane-bound to activate signaling at a short range from their source. |
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| Beschreibung: | Gesehen am 31.10.2019 |
| Beschreibung: | Online Resource |
| ISSN: | 1878-1551 |
| DOI: | 10.1016/j.devcel.2016.02.018 |