Assessment of straylight and the modulation transfer function of intraocular lenses with centrally localized opacification associated with the intraocular injection of gas
Purpose - To assess the optical quality of intraocular lenses (IOLs) explanted because of opacification after the intraocular injection of gas. - Setting - David J. Apple Laboratory, Heidelberg, Germany. - Design - Experimental study. - Methods - Four hydrophilic acrylic IOLs were studied, each with...
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| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
15 June 2018
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| In: |
Journal of cataract and refractive surgery
Year: 2018, Jahrgang: 44, Heft: 5, Pages: 615-622 |
| ISSN: | 1873-4502 |
| DOI: | 10.1016/j.jcrs.2018.01.033 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1016/j.jcrs.2018.01.033 Verlag: http://www.sciencedirect.com/science/article/pii/S0886335018302906 
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| Verfasserangaben: | Grzegorz Łabuz, Timur M. Yildirim, Thomas J.T.P. van den Berg, Ramin Khoramnia, Gerd U. Auffarth |
| Zusammenfassung: | Purpose - To assess the optical quality of intraocular lenses (IOLs) explanted because of opacification after the intraocular injection of gas. - Setting - David J. Apple Laboratory, Heidelberg, Germany. - Design - Experimental study. - Methods - Four hydrophilic acrylic IOLs were studied, each with a centrally localized round opacification pattern associated with the intraocular use of gas. Laboratory analysis included gross examination with a light microscope, followed by alizarin and von Kossa staining. Optical quality was assessed by examining the modulation transfer function (MTF) and straylight. Results were compared with those of a control IOL and normative data for straylight of the crystalline lens. The following parameters were derived from image analysis: opacified surface fraction, light loss in the opacified surface, and the area and number of granules. The relationship between straylight increase and those parameters was studied. - Results - Fine granules were identified on the IOL surface and subsurface. The granules stained positive for calcium, and the MTF levels of 2 IOLs dropped markedly. The other 2 showed relatively minor changes. The straylight was extremely increased in 3 IOLs up to (and above) a level of that of a cataractous lens. A proportional relationship was found between straylight and the morphological parameters from image analysis. - Conclusions - Intraocular lenses with centrally localized opacification have a strong potential for deteriorating optical performance. However, the optical quality might differ depending on the morphology of opacification. A serious straylight increase was found in most of these IOLs, suggesting that affected patients may suffer from glare-related symptoms. |
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| Beschreibung: | Gesehen am 04.11.2019 |
| Beschreibung: | Online Resource |
| ISSN: | 1873-4502 |
| DOI: | 10.1016/j.jcrs.2018.01.033 |