MEST mediates the impact of prenatal bisphenol A exposure on long-term body weight development
Exposure to endocrine-disrupting chemicals can alter normal physiology and increase susceptibility to non-communicable diseases like obesity. Especially the prenatal and early postnatal period is highly vulnerable to adverse effects by environmental exposure, promoting developmental reprogramming by...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
20 April 2018
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| In: |
Clinical epigenetics
Year: 2018, Volume: 10, Issue: 1 |
| ISSN: | 1868-7083 |
| DOI: | 10.1186/s13148-018-0478-z |
| Online Access: | Verlag, Volltext: https://doi.org/10.1186/s13148-018-0478-z |
| Author Notes: | Kristin M. Junge, Beate Leppert, Susanne Jahreis, Dirk K. Wissenbach, Ralph Feltens, Konrad Grützmann, Loreen Thürmann, Tobias Bauer, Naveed Ishaque, Matthias Schick, Melanie Bewerunge-Hudler, Stefan Röder, Mario Bauer, Angela Schulz, Michael Borte, Kathrin Landgraf, Antje Körner, Wieland Kiess, Martin von Bergen, Gabriele I. Stangl, Saskia Trump, Roland Eils, Tobias Polte and Irina Lehmann |
| Summary: | Exposure to endocrine-disrupting chemicals can alter normal physiology and increase susceptibility to non-communicable diseases like obesity. Especially the prenatal and early postnatal period is highly vulnerable to adverse effects by environmental exposure, promoting developmental reprogramming by epigenetic alterations. To obtain a deeper insight into the role of prenatal bisphenol A (BPA) exposure in children’s overweight development, we combine epidemiological data with experimental models and BPA-dependent DNA methylation changes. |
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| Item Description: | Gesehen am 07.11.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1868-7083 |
| DOI: | 10.1186/s13148-018-0478-z |