Distal pancreatectomy with celiac axis resection (DP-CAR) for pancreatic cancer: how I do it
Approximately 30% of all pancreatic cancer patients have locally advanced (AJCC stage 3) disease. A sub-group of these patients - where the cancer only involves the celiac axis - may benefit from distal pancreatectomy with celiac axis resection (DP-CAR). Previous studies have shown that DP-CAR offer...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
13 August 2018
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| In: |
Journal of gastrointestinal surgery
Year: 2018, Volume: 22, Issue: 10, Pages: 1804-1810 |
| ISSN: | 1873-4626 |
| DOI: | 10.1007/s11605-018-3894-7 |
| Online Access: | Resolving-System, Volltext: https://doi.org/10.1007/s11605-018-3894-7 Verlag: https://link.springer.com/article/10.1007%2Fs11605-018-3894-7 
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| Author Notes: | Sjors Klompmaker, Ugo Boggi, Thilo Hackert, Roberto Salvia, Matthew Weiss, Hiroki Yamaue, Herbert J. Zeh, Marc G. Besselink |
| Summary: | Approximately 30% of all pancreatic cancer patients have locally advanced (AJCC stage 3) disease. A sub-group of these patients - where the cancer only involves the celiac axis - may benefit from distal pancreatectomy with celiac axis resection (DP-CAR). Previous studies have shown that DP-CAR offers a survival benefit to a selected group of patients with otherwise unresectable pancreatic cancer, when performed by experienced pancreatic cancer treatment teams at high-volume centers. This article proposes a standardized approach to DP-CAR, including routine neoadjuvant (FOLFIRINOX) chemotherapy. This approach to selecting patients and performing DP-CAR has the potential to improve short-term outcomes and overall survival in selected patients, but it should be reserved for high-volume centers. |
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| Item Description: | Gesehen am 11.11.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1873-4626 |
| DOI: | 10.1007/s11605-018-3894-7 |