Sellar region atypical teratoid/rhabdoid tumors (ATRT) in adults display DNA methylation profiles of the ATRT-MYC subgroup

Atypical teratoid/rhabdoid tumor (ATRT) is a highly malignant brain tumor predominantly encountered in infants. Mutations of the SMARCB1 gene are the characteristic genetic lesion. A small group of ATRT stands out clinically, because these tumors are located in the sellar region of adults. To invest

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Bibliographic Details
Main Authors: Johann, Pascal-David (Author) , Bens, Susanne (Author) , Oyen, Florian (Author) , Wagener, Rabea (Author) , Giannini, Caterina (Author) , Perry, Arie (Author) , Raisanen, Jack (Author) , Reis, Gerald (Author) , Nobusawa, Sumihito (Author) , Arita, Kazunori (Author) , Felsberg, Jörg (Author) , Reifenberger, Guido (Author) , Agaimy, Abbas (Author) , Buslei, Rolf (Author) , Capper, David (Author) , Pfister, Stefan (Author) , Schneppenheim, Reinhard (Author) , Siebert, Reiner (Author) , Frühwald, Michael (Author) , Paulus, Werner (Author) , Kool, Marcel (Author) , Hasselblatt, Martin (Author)
Format: Article (Journal)
Language:English
Published: April 2018
In: The American journal of surgical pathology
Year: 2018, Volume: 42, Issue: 4, Pages: 506-511
ISSN:1532-0979
DOI:10.1097/PAS.0000000000001023
Online Access:Verlag, Volltext: https://doi.org/10.1097/PAS.0000000000001023
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Author Notes:Pascal D. Johann, MD, Susanne Bens, MD, Florian Oyen, Rabea Wagener, PhD, Caterina Giannini, MD, Arie Perry, MD, Jack M. Raisanen, MD, Gerald F. Reis, MD, PhD, Sumihito Nobusawa, MD, Kazunori Arita, MD, Jörg Felsberg, MD, Guido Reifenberger, MD, Abbas Agaimy, MD, Rolf Buslei, MD, David Capper, MD, Stefan M. Pfister, MD, Reinhard Schneppenheim, MD, PhD, Reiner Siebert, MD, Michael C. Frühwald, MD, PhD, Werner Paulus, MD, Marcel Kool, PhD, and Martin Hasselblatt
Description
Summary:Atypical teratoid/rhabdoid tumor (ATRT) is a highly malignant brain tumor predominantly encountered in infants. Mutations of the SMARCB1 gene are the characteristic genetic lesion. A small group of ATRT stands out clinically, because these tumors are located in the sellar region of adults. To invest
Item Description:Gesehen am 12.11.2019
Physical Description:Online Resource
ISSN:1532-0979
DOI:10.1097/PAS.0000000000001023