Posterior fundus hemorrhages: frequency and associated factors: the Beijing eye ytudy
Purpose: To examine frequency and associations of retinal hemorrhages. - Methods: The population-based Beijing Eye Study included 3,468 individuals. Monoscopic fundus photographs were examined for hemorrhages. - Results: Retinal hemorrhages were detected in 515 eyes (429 individuals) (preval...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
June 2019
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| In: |
Retina
Year: 2019, Volume: 39, Issue: 6, Pages: 1206-1215 |
| ISSN: | 1539-2864 |
| DOI: | 10.1097/IAE.0000000000002122 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1097/IAE.0000000000002122 Verlag: https://journals.lww.com/retinajournal/Abstract/2019/06000/POSTERIOR_FUNDUS_HEMORRHAGES__Frequency_and.23.aspx 
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| Author Notes: | Jin Qiong Zhou, Ya Xing Wang, Liang Xu, Liang Zhao, Shuang Wang, Jie Xu, Qi Sheng You, Hua Yang, Wen Bin Wei, Jost B. Jonas |
| Summary: | Purpose: To examine frequency and associations of retinal hemorrhages. - Methods: The population-based Beijing Eye Study included 3,468 individuals. Monoscopic fundus photographs were examined for hemorrhages. - Results: Retinal hemorrhages were detected in 515 eyes (429 individuals) (prevalence: 7.6%; 95% confidence interval [CI]: 7.0-8.0 per eye; 12.7%; 95% CI: 11.7-13.7 per person). Higher prevalence of retinal hemorrhages was correlated (multivariate analysis) with higher systolic blood pressure (P < 0.001; odds ratio: 1.02; 95% CI: 1.01-1.03), higher prevalence of diabetic retinopathy (P < 0.001; odds ratio: 121; 95% CI: 61-240), and higher prevalence of retinal vein occlusions (P < 0.001; odds ratio: 27; 95% CI: 17-42). Retinal hemorrhages were due to diabetic retinopathy (189 [36.7%] eyes), retinal vein occlusions (n = 65 [12.6%]), posterior vitreous detachment (n = 23 [4.5%]), glaucoma (n = 14 [2.7%]), exudative age-related macular degeneration (n = 8 [1.6%]), hypertensive retinopathy (n = 10 [1.9%]), and exudative myopic maculopathy (n = 1 [0.2%]). Retinal hemorrhages without evident ocular cause (“NOH”) were detected in 204 (3.0%) eyes (or 39.6% of all retinal hemorrhages). Higher prevalence of NOHs was correlated with higher systolic blood pressure (P < 0.001; odds ratio: 1.02; 95% CI: 1.01-1.03) after adjusting for blood glucose concentration and prevalence of cortical cataract. - Conclusion: In a population-based recruited cohort of individuals aged 50+ years, prevalence of any fundus hemorrhage was about 8% per eye and 13% per individual. Approximately 60% of the hemorrhages were due to ocular reasons, mainly diabetic retinopathy, retinal vein occlusions, and posterior vitreous detachment, whereas 40% of the bleedings were not evidently associated with ophthalmologic causes but strongly with elevated systolic blood pressure. |
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| Item Description: | Gesehen am 18.11.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1539-2864 |
| DOI: | 10.1097/IAE.0000000000002122 |