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Definitive radiotherapy vs. postoperative radiotherapy for lower gingival carcinomas of the mandible: a asingle-center report about outcome and toxicity

Purpose To assess radiotherapy (RT) outcomes in patients with gingival carcinoma and growth up to or involvement of the lower jaw bone. Methods This was a retrospective analysis of 51 patients with squamous cell carcinomas of the gingiva. Patients received definitive (group 1, 31.4%) or postoperative...

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Main Authors: Uzun-Lang, Kristin (Author) , Akbaba, Sati (Author) , Held, Thomas (Author) , Kargus, Steffen (Author) , Horn, Dominik (Author) , Bougatf, Nina (Author) , Bernhardt, Denise (Author) , Freier, Kolja (Author) , Rieken, Stefan (Author) , Debus, Jürgen (Author) , Adeberg, Sebastian (Author)
Format: Article (Journal)
Language:English
Published: 02 July 2019
In: Strahlentherapie und Onkologie
Year: 2019, Volume: 195, Issue: 9, Pages: 819-829
ISSN:1439-099X
DOI:10.1007/s00066-019-01484-z
Online Access:Verlag, Volltext: https://doi.org/10.1007/s00066-019-01484-z
Verlag: http://link.springer.com/10.1007/s00066-019-01484-z
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Author Notes:Kristin Lang, Sati Akbaba, Thomas Held, Steffen Kargus, Dominik Horn, Nina Bougatf, Denise Bernhardt, Kolja Freier, Stefan Rieken, Jürgen Debus, Sebastian Adeberg
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Summary:Purpose To assess radiotherapy (RT) outcomes in patients with gingival carcinoma and growth up to or involvement of the lower jaw bone. Methods This was a retrospective analysis of 51 patients with squamous cell carcinomas of the gingiva. Patients received definitive (group 1, 31.4%) or postoperative (group 2, 66.7%) RT between 2005 and 2017 at the Department of Radiation Oncology, University Hospital Heidelberg. The primary endpoint was overall survival (OS) in both treatment groups. Other endpoints were local-disease-free survival (LDFS), progression-free survival (PFS) and treatment-related toxicity (Common Terminology Criteria for Adverse Events, CTCAE, Version 4.03).
Item Description:Gesehen am 19.11.2019
Physical Description:Online Resource
ISSN:1439-099X
DOI:10.1007/s00066-019-01484-z

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