A common ground for pain and depression
Chronic pain is associated with anxio-depressive comorbidities, but the neuroanatomical substrates remain unknown. A specific serotonergic pathway from the dorsal raphe nucleus to the lateral habenula via the central amygdala is now uncovered as a key neural circuit governing comorbid depressive sym...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
27 August 2019
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| In: |
Nature neuroscience
Year: 2019, Volume: 22, Issue: 10, Pages: 1612-1614 |
| ISSN: | 1546-1726 |
| DOI: | 10.1038/s41593-019-0499-8 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1038/s41593-019-0499-8 Verlag, Volltext: https://www.nature.com/articles/s41593-019-0499-8 |
| Author Notes: | Anke Tappe-Theodor and Rohini Kuner |
| Summary: | Chronic pain is associated with anxio-depressive comorbidities, but the neuroanatomical substrates remain unknown. A specific serotonergic pathway from the dorsal raphe nucleus to the lateral habenula via the central amygdala is now uncovered as a key neural circuit governing comorbid depressive symptoms in chronic pain. |
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| Item Description: | Gesehen am 21.11.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1546-1726 |
| DOI: | 10.1038/s41593-019-0499-8 |