A common ground for pain and depression

Chronic pain is associated with anxio-depressive comorbidities, but the neuroanatomical substrates remain unknown. A specific serotonergic pathway from the dorsal raphe nucleus to the lateral habenula via the central amygdala is now uncovered as a key neural circuit governing comorbid depressive sym...

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Bibliographic Details
Main Authors: Tappe-Theodor, Anke (Author) , Kuner, Rohini (Author)
Format: Article (Journal)
Language:English
Published: 27 August 2019
In: Nature neuroscience
Year: 2019, Volume: 22, Issue: 10, Pages: 1612-1614
ISSN:1546-1726
DOI:10.1038/s41593-019-0499-8
Online Access:Verlag, Volltext: https://doi.org/10.1038/s41593-019-0499-8
Verlag, Volltext: https://www.nature.com/articles/s41593-019-0499-8
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Author Notes:Anke Tappe-Theodor and Rohini Kuner
Description
Summary:Chronic pain is associated with anxio-depressive comorbidities, but the neuroanatomical substrates remain unknown. A specific serotonergic pathway from the dorsal raphe nucleus to the lateral habenula via the central amygdala is now uncovered as a key neural circuit governing comorbid depressive symptoms in chronic pain.
Item Description:Gesehen am 21.11.2019
Physical Description:Online Resource
ISSN:1546-1726
DOI:10.1038/s41593-019-0499-8