A common ground for pain and depression

Chronic pain is associated with anxio-depressive comorbidities, but the neuroanatomical substrates remain unknown. A specific serotonergic pathway from the dorsal raphe nucleus to the lateral habenula via the central amygdala is now uncovered as a key neural circuit governing comorbid depressive sym...

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Hauptverfasser: Tappe-Theodor, Anke (VerfasserIn) , Kuner, Rohini (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 27 August 2019
In: Nature neuroscience
Year: 2019, Jahrgang: 22, Heft: 10, Pages: 1612-1614
ISSN:1546-1726
DOI:10.1038/s41593-019-0499-8
Online-Zugang:Verlag, Volltext: https://doi.org/10.1038/s41593-019-0499-8
Verlag, Volltext: https://www.nature.com/articles/s41593-019-0499-8
Volltext
Verfasserangaben:Anke Tappe-Theodor and Rohini Kuner
Beschreibung
Zusammenfassung:Chronic pain is associated with anxio-depressive comorbidities, but the neuroanatomical substrates remain unknown. A specific serotonergic pathway from the dorsal raphe nucleus to the lateral habenula via the central amygdala is now uncovered as a key neural circuit governing comorbid depressive symptoms in chronic pain.
Beschreibung:Gesehen am 21.11.2019
Beschreibung:Online Resource
ISSN:1546-1726
DOI:10.1038/s41593-019-0499-8