Principles and applications of optogenetics in developmental biology
Skip to Next Section - The development of multicellular organisms is controlled by highly dynamic molecular and cellular processes organized in spatially restricted patterns. Recent advances in optogenetics are allowing protein function to be controlled with the precision of a pulse of laser light i...
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| Main Authors: | , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
22 October 2019
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| In: |
Development
Year: 2019, Volume: 146, Issue: 20 |
| ISSN: | 1477-9129 |
| DOI: | 10.1242/dev.175067 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1242/dev.175067 Verlag, Volltext: https://dev.biologists.org/content/146/20/dev175067 |
| Author Notes: | Daniel Krueger, Emiliano Izquierdo, Ranjith Viswanathan, Jonas Hartmann, Cristina Pallares Cartes and Stefano De Renzis |
| Summary: | Skip to Next Section - The development of multicellular organisms is controlled by highly dynamic molecular and cellular processes organized in spatially restricted patterns. Recent advances in optogenetics are allowing protein function to be controlled with the precision of a pulse of laser light in vivo, providing a powerful new tool to perturb developmental processes at a wide range of spatiotemporal scales. In this Primer, we describe the most commonly used optogenetic tools, their application in developmental biology and in the nascent field of synthetic morphogenesis. |
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| Item Description: | Gesehen am 21.11.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1477-9129 |
| DOI: | 10.1242/dev.175067 |