Longitudinal evaluation of plasma concentrations of presepsin in patients after severe trauma: a prospective observational study
The high mortality rate of patients suffering from severe trauma is based not only on the mechanism of injury, but also on the higher risk for development of subsequent infections. Therefore, the early recognition of infection after severe trauma is of particular importance for patient outcome. Howe...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
1 Jul 2018
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| In: |
Surgical infections
Year: 2018, Volume: 19, Issue: 5, Pages: 480-487 |
| ISSN: | 1557-8674 |
| DOI: | 10.1089/sur.2017.266 |
| Online Access: | Resolving-System, Volltext: https://doi.org/10.1089/sur.2017.266 Verlag: https://www.liebertpub.com/doi/10.1089/sur.2017.266 
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| Author Notes: | Christian Koch, Sophie Ruhrmann, Michael Pöhlmann, Emmanuel Schneck, Borros Arneth, Thomas Zajonz, Michael Sander, Markus A. Weigand, Florian Uhle |
| Summary: | The high mortality rate of patients suffering from severe trauma is based not only on the mechanism of injury, but also on the higher risk for development of subsequent infections. Therefore, the early recognition of infection after severe trauma is of particular importance for patient outcome. However, early diagnosis is often masked by the consequences of the sterile, damage-triggered immune response. Our study sought to analyze the course of soluble CD14-subtype (sCD14-ST, presepsin) compared with clinically established inflammatory and infectious biomarkers in a cohort of patients with severe trauma. |
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| Item Description: | Gesehen am 27.11.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1557-8674 |
| DOI: | 10.1089/sur.2017.266 |