Regiocontrolled synthesis of fused heterocyclic skeletons containing yyranocoumarin backbones
A convenient, highly efficient regioselective strategy for the synthesis of chromeno[3′,4′-5,6]pyrano[2,3-b]quinoline is described. The reaction proceed through three-component reaction of 2-chloro-3-formylquinoline, malononitrile and 4-hydroxycoumarin in the presence of 10 mole% diammonium hydrogen...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
16 August 2019
|
| In: |
ChemistrySelect
Year: 2019, Volume: 4, Issue: 31, Pages: 8921-8924 |
| ISSN: | 2365-6549 |
| DOI: | 10.1002/slct.201901788 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1002/slct.201901788 Verlag: https://onlinelibrary.wiley.com/doi/abs/10.1002/slct.201901788 
|
| Author Notes: | Saeed Balalaie, Yasaman Doroudian, Nahid Zarezadeh, Hossein Zahedian Tejeneki, and Frank Rominger |
| Summary: | A convenient, highly efficient regioselective strategy for the synthesis of chromeno[3′,4′-5,6]pyrano[2,3-b]quinoline is described. The reaction proceed through three-component reaction of 2-chloro-3-formylquinoline, malononitrile and 4-hydroxycoumarin in the presence of 10 mole% diammonium hydrogen phosphate (DAHP) in aqueous media at room temperature. It is a domino Knoevenagel condensation/ Michael addition and regiocontrolled cyclization reaction. |
|---|---|
| Item Description: | Gesehen am 03.12.2019 |
| Physical Description: | Online Resource |
| ISSN: | 2365-6549 |
| DOI: | 10.1002/slct.201901788 |