Regiocontrolled synthesis of fused heterocyclic skeletons containing yyranocoumarin backbones

A convenient, highly efficient regioselective strategy for the synthesis of chromeno[3′,4′-5,6]pyrano[2,3-b]quinoline is described. The reaction proceed through three-component reaction of 2-chloro-3-formylquinoline, malononitrile and 4-hydroxycoumarin in the presence of 10 mole% diammonium hydrogen...

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Hauptverfasser: Balalaie, Saeed (Verfasst von) , Rominger, Frank (Verfasst von)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 16 August 2019
In: ChemistrySelect
Year: 2019, Jahrgang: 4, Heft: 31, Pages: 8921-8924
ISSN:2365-6549
DOI:10.1002/slct.201901788
Online-Zugang:Verlag, Volltext: https://doi.org/10.1002/slct.201901788
Verlag: https://onlinelibrary.wiley.com/doi/abs/10.1002/slct.201901788
Volltext
Verfasserangaben:Saeed Balalaie, Yasaman Doroudian, Nahid Zarezadeh, Hossein Zahedian Tejeneki, and Frank Rominger
Beschreibung
Zusammenfassung:A convenient, highly efficient regioselective strategy for the synthesis of chromeno[3′,4′-5,6]pyrano[2,3-b]quinoline is described. The reaction proceed through three-component reaction of 2-chloro-3-formylquinoline, malononitrile and 4-hydroxycoumarin in the presence of 10 mole% diammonium hydrogen phosphate (DAHP) in aqueous media at room temperature. It is a domino Knoevenagel condensation/ Michael addition and regiocontrolled cyclization reaction.
Beschreibung:Gesehen am 03.12.2019
Beschreibung:Online Resource
ISSN:2365-6549
DOI:10.1002/slct.201901788