Regiocontrolled synthesis of fused heterocyclic skeletons containing yyranocoumarin backbones
A convenient, highly efficient regioselective strategy for the synthesis of chromeno[3′,4′-5,6]pyrano[2,3-b]quinoline is described. The reaction proceed through three-component reaction of 2-chloro-3-formylquinoline, malononitrile and 4-hydroxycoumarin in the presence of 10 mole% diammonium hydrogen...
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
16 August 2019
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| In: |
ChemistrySelect
Year: 2019, Jahrgang: 4, Heft: 31, Pages: 8921-8924 |
| ISSN: | 2365-6549 |
| DOI: | 10.1002/slct.201901788 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1002/slct.201901788 Verlag: https://onlinelibrary.wiley.com/doi/abs/10.1002/slct.201901788 |
| Verfasserangaben: | Saeed Balalaie, Yasaman Doroudian, Nahid Zarezadeh, Hossein Zahedian Tejeneki, and Frank Rominger |
| Zusammenfassung: | A convenient, highly efficient regioselective strategy for the synthesis of chromeno[3′,4′-5,6]pyrano[2,3-b]quinoline is described. The reaction proceed through three-component reaction of 2-chloro-3-formylquinoline, malononitrile and 4-hydroxycoumarin in the presence of 10 mole% diammonium hydrogen phosphate (DAHP) in aqueous media at room temperature. It is a domino Knoevenagel condensation/ Michael addition and regiocontrolled cyclization reaction. |
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| Beschreibung: | Gesehen am 03.12.2019 |
| Beschreibung: | Online Resource |
| ISSN: | 2365-6549 |
| DOI: | 10.1002/slct.201901788 |