The reimplantation valve-sparing aortic root replacement technique for patients with Marfan syndrome: a single-center experience
Valve-sparing aortic root replacement (VSARR) through reimplantation technique is widely regarded as optimal surgical approach for Marfan syndrome (MFS) patients. Perioperative and long-term data from all MFS patients undergoing VSARR using David’s technique at our center from 2007-2018 were analyze...
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| Main Authors: | , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
19 August 2019
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| In: |
Scientific reports
Year: 2019, Volume: 9, Pages: 1-8 |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/s41598-019-48572-9 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1038/s41598-019-48572-9 Verlag: https://www.nature.com/articles/s41598-019-48572-9 
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| Author Notes: | Jamila Kremer, Mina Farag, Marcin Zaradzki, Gabor Szabó, Arjang Ruhparwar, Klaus Kallenbach, Matthias Karck & Rawa Arif |
| Summary: | Valve-sparing aortic root replacement (VSARR) through reimplantation technique is widely regarded as optimal surgical approach for Marfan syndrome (MFS) patients. Perioperative and long-term data from all MFS patients undergoing VSARR using David’s technique at our center from 2007-2018 were analyzed. We included 56 patients with a mean age of 32.3 ± 12.3 years. Logistic EuroSCORE was 7.96 ± 5.2. Among others concomitant surgical procedures included aortic arch surgery (8.9%), mitral valve repair (23.2%) and replacement (1.7%). There were no operative deaths, nor in-hospital-mortality. One patient underwent re-exploration for bleeding, dialysis and pacemaker implantation was required in one case each. There was no occurrence of low-output syndrome nor neurological complications. Significant gender differences were not found, except for intraoperative blood transfusion occurring significantly more often in the female gender (p = 0.009). Despite significantly longer procedural times, concomitant surgery did not negatively impact overall outcome. Freedom of reoperation of the aortic root was 100% at 1 year, 97.7% at 8 years. Until last follow-up (61 ± 38 month) all patients survived, with no evidence of endocarditis. We emphasize once more that VSARR using David’s procedure is a safe method for MFS patients with excellent long-term results even if concomitant procedures are performed. |
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| Item Description: | Gesehen am 05.12.2019 |
| Physical Description: | Online Resource |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/s41598-019-48572-9 |