Cover Image

Unattached kinetochores drive their own capturing by sequestering a CLASP

Kinetochores (KT) that are not attached to microtubules prevent chromosome missegregation via the spindle assembly checkpoint. Here the authors show that Mps1 localizes Stu1 at unattached KTs together with Slk19, causing a reorganization of the nuclear MT network that favors the capturing of unattac...

Full description

Saved in:
Bibliographic Details
Main Authors: Kolenda, Caroline (Author) , Ortiz, Jennifer (Author) , Pelzl, Marina (Author) , Norell, Sarina (Author) , Schmeiser, Verena (Author) , Lechner, Johannes (Author)
Format: Article (Journal)
Language:English
Published: 28 February 2018
In: Nature Communications
Year: 2018, Volume: 9
ISSN:2041-1723
DOI:10.1038/s41467-018-03108-z
Online Access:Resolving-System, Volltext: https://doi.org/10.1038/s41467-018-03108-z
Verlag: https://www.nature.com/articles/s41467-018-03108-z
Get full text
Author Notes:Caroline Kolenda, Jennifer Ortiz, Marina Pelzl, Sarina Norell, Verena Schmeiser & Johannes Lechner
Description
Summary:Kinetochores (KT) that are not attached to microtubules prevent chromosome missegregation via the spindle assembly checkpoint. Here the authors show that Mps1 localizes Stu1 at unattached KTs together with Slk19, causing a reorganization of the nuclear MT network that favors the capturing of unattached KT.
Item Description:Gesehen am 11.12.2019
Physical Description:Online Resource
ISSN:2041-1723
DOI:10.1038/s41467-018-03108-z

Similar Items