c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells
The transcription factor c-Maf controls IL-10 production in T cells. O’Garra and colleagues use systems and in vivo functional analysis of T cell subsets to reveal distinct context-specific roles for c-Maf.
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
16 April 2018
|
| In: |
Nature immunology
Year: 2018, Volume: 19, Issue: 5, Pages: 497-507 |
| ISSN: | 1529-2916 |
| DOI: | 10.1038/s41590-018-0083-5 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1038/s41590-018-0083-5 Verlag: https://www.nature.com/articles/s41590-018-0083-5 
|
| Author Notes: | Leona Gabryšová, Marisol Alvarez-Martinez, Raphaëlle Luisier, Luke S. Cox, Jan Sodenkamp, Caroline Hosking, Damián Pérez-Mazliah, Charlotte Whicher, Yashaswini Kannan, Krzysztof Potempa, Xuemei Wu, Leena Bhaw, Hagen Wende, Michael H. Sieweke, Greg Elgar, Mark Wilson, James Briscoe, Vicki Metzis, Jean Langhorne, Nicholas M. Luscombe and Anne O’Garra |
| Summary: | The transcription factor c-Maf controls IL-10 production in T cells. O’Garra and colleagues use systems and in vivo functional analysis of T cell subsets to reveal distinct context-specific roles for c-Maf. |
|---|---|
| Item Description: | Gesehen am 13.12.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1529-2916 |
| DOI: | 10.1038/s41590-018-0083-5 |