c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells
The transcription factor c-Maf controls IL-10 production in T cells. O’Garra and colleagues use systems and in vivo functional analysis of T cell subsets to reveal distinct context-specific roles for c-Maf.
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
16 April 2018
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| In: |
Nature immunology
Year: 2018, Jahrgang: 19, Heft: 5, Pages: 497-507 |
| ISSN: | 1529-2916 |
| DOI: | 10.1038/s41590-018-0083-5 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1038/s41590-018-0083-5 Verlag: https://www.nature.com/articles/s41590-018-0083-5 
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| Verfasserangaben: | Leona Gabryšová, Marisol Alvarez-Martinez, Raphaëlle Luisier, Luke S. Cox, Jan Sodenkamp, Caroline Hosking, Damián Pérez-Mazliah, Charlotte Whicher, Yashaswini Kannan, Krzysztof Potempa, Xuemei Wu, Leena Bhaw, Hagen Wende, Michael H. Sieweke, Greg Elgar, Mark Wilson, James Briscoe, Vicki Metzis, Jean Langhorne, Nicholas M. Luscombe and Anne O’Garra |
| Zusammenfassung: | The transcription factor c-Maf controls IL-10 production in T cells. O’Garra and colleagues use systems and in vivo functional analysis of T cell subsets to reveal distinct context-specific roles for c-Maf. |
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| Beschreibung: | Gesehen am 13.12.2019 |
| Beschreibung: | Online Resource |
| ISSN: | 1529-2916 |
| DOI: | 10.1038/s41590-018-0083-5 |