c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells

The transcription factor c-Maf controls IL-10 production in T cells. O’Garra and colleagues use systems and in vivo functional analysis of T cell subsets to reveal distinct context-specific roles for c-Maf.

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Bibliographic Details
Main Authors: Gabryšová, Leona (Author) , Wende, Hagen (Author)
Format: Article (Journal)
Language:English
Published: 16 April 2018
In: Nature immunology
Year: 2018, Volume: 19, Issue: 5, Pages: 497-507
ISSN:1529-2916
DOI:10.1038/s41590-018-0083-5
Online Access:Verlag, Volltext: https://doi.org/10.1038/s41590-018-0083-5
Verlag: https://www.nature.com/articles/s41590-018-0083-5
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Author Notes:Leona Gabryšová, Marisol Alvarez-Martinez, Raphaëlle Luisier, Luke S. Cox, Jan Sodenkamp, Caroline Hosking, Damián Pérez-Mazliah, Charlotte Whicher, Yashaswini Kannan, Krzysztof Potempa, Xuemei Wu, Leena Bhaw, Hagen Wende, Michael H. Sieweke, Greg Elgar, Mark Wilson, James Briscoe, Vicki Metzis, Jean Langhorne, Nicholas M. Luscombe and Anne O’Garra

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