Similarities in the computed tomography appearance in α1-antitrypsin deficiency and smoking-related chronic obstructive pulmonary disease in a smoking collective

Emphysematous destruction of lung parenchyma visible in computed tomography (CT) can be attributed to chronic obstructive pulmonary disease (COPD) or to α1-antitrypsin deficiency (AATD). We evaluated if visual semiquantitative phenotyping of CT data helps identifying individuals with AATD in a group...

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Bibliographic Details
Main Authors: Konietzke, Philip (Author) , Jobst, Bertram (Author) , Wagner, Willi Linus (Author) , Kauczor, Hans-Ulrich (Author) , Wielpütz, Mark Oliver (Author)
Format: Article (Journal)
Language:English
Published: June 25, 2018
In: Respiration
Year: 2018, Volume: 96, Issue: 3, Pages: 231-239
ISSN:1423-0356
DOI:10.1159/000489177
Online Access:Resolving-System, Volltext: https://doi.org/10.1159/000489177
Verlag: https://www.karger.com/Article/FullText/489177
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Author Notes:Philip Konietzke, Bertram Jobst, Willi L. Wagner, Inga Jarosch, Ralph Graber, Klaus Kenn, Hans-Ulrich Kauczor, Mark O. Wielpütz
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Summary:Emphysematous destruction of lung parenchyma visible in computed tomography (CT) can be attributed to chronic obstructive pulmonary disease (COPD) or to α1-antitrypsin deficiency (AATD). We evaluated if visual semiquantitative phenotyping of CT data helps identifying individuals with AATD in a group of smokers with severe emphysema and airflow limitation.
Item Description:Gesehen am 21.01.2020
Physical Description:Online Resource
ISSN:1423-0356
DOI:10.1159/000489177