Incomplete structural reverse remodeling from late-stage left ventricular hypertrophy impedes the recovery of diastolic but not systolic dysfunction in rats

Objective:Pressure overload-induced left ventricular myocardial hypertrophy (LVH) regresses after pressure unloading. However, distinct structural alterations become less reversible during the progression of LVH, which might influence the restoration of cardiac function. Here, we investigated how a

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Main Authors: Ruppert, Mihály (Author) , Korkmaz-İçöz, Sevil (Author) , Loganathan, Sivakkanan (Author) , Sayour, Alex Ali (Author) , Karck, Matthias (Author) , Szabó, Gábor (Author)
Format: Article (Journal)
Language:English
Published: June 2019
In: Journal of hypertension
Year: 2019, Volume: 37, Issue: 6, Pages: 1200-1212
ISSN:1473-5598
DOI:10.1097/HJH.0000000000002042
Online Access:Verlag, Volltext: https://doi.org/10.1097/HJH.0000000000002042
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Author Notes:Mihály Ruppert, Sevil Korkmaz-Icöz, Sivakkanan Loganathan, Weipeng Jiang, Attila Oláh, Alex Sayour, Bálint Barta, Christian Karime, Béla Merkely, Matthias Karck, Tamás Radovits, Gábor Szabó
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Summary:Objective:Pressure overload-induced left ventricular myocardial hypertrophy (LVH) regresses after pressure unloading. However, distinct structural alterations become less reversible during the progression of LVH, which might influence the restoration of cardiac function. Here, we investigated how a
Item Description:Gesehen am 23.01.2020
Physical Description:Online Resource
ISSN:1473-5598
DOI:10.1097/HJH.0000000000002042