MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms
MacroH2A histone variants suppress tumor progression and act as epigenetic barriers to induced pluripotency. How they impart their influence on chromatin plasticity is not well understood. Here, we analyze how the different domains of macroH2A proteins contribute to chromatin structure and dynamics.
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
3 September 2018
|
| In: |
EMBO reports
Year: 2018, Volume: 19, Issue: 10 |
| ISSN: | 1469-3178 |
| DOI: | 10.15252/embr.201744445 |
| Online Access: | Resolving-System, Volltext: https://doi.org/10.15252/embr.201744445 Verlag: https://www.embopress.org/doi/full/10.15252/embr.201744445 
|
| Author Notes: | Marek Kozlowski, David Corujo, Michael Hothorn, Iva Guberovic, Imke K Mandemaker, Charlotte Blessing, Judith Sporn, Arturo Gutierrez-Triana, Rebecca Smith, Thomas Portmann, Mathias Treier, Klaus Scheffzek, Sebastien Huet, Gyula Timinszky, Marcus Buschbeck & Andreas G Ladurner |
| Summary: | MacroH2A histone variants suppress tumor progression and act as epigenetic barriers to induced pluripotency. How they impart their influence on chromatin plasticity is not well understood. Here, we analyze how the different domains of macroH2A proteins contribute to chromatin structure and dynamics. |
|---|---|
| Item Description: | Gesehen am 30.01.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1469-3178 |
| DOI: | 10.15252/embr.201744445 |